Fetal microchimerism is the presence of cells that originate from another individual and are present in the body of an individual other than their source. These cells can be either benign or malignant, and they may persist in the host for many years after the initial exposure. Fetal microchimerism has been implicated in a number of diseases and conditions, including autoimmune diseases, cancer, and transplant rejection.
While the exact mechanisms by which fetal microchimerism leads to disease are not fully understood, it is thought that these cells may interact with the immune system of the host, leading to inflammation or other problems. Additionally, fetal microchimeric cells have been shown to have abnormal growth properties that may contribute to tumor formation. Overall, fetal microchimerism is a complex phenomenon with far-reaching implications for human health.
Research on fetal microchimerism is ongoing, and future studies will likely shed more light on the role these cells play in human health and disease. In the meantime, clinicians should be aware of the potential risks associated with this phenomenon and take appropriate steps to protect their patients.