Proteomics is the large-scale study of proteins, particularly their structures and functions. Proteomic analyses can be used to identify and characterize unknown proteins, to understand the functions of known proteins, and to detect changes in protein abundance or activity in response to various stimuli. Proteomic technologies are increasingly used in biomedical research and drug development.
Proteins are the major structural and functional components of cells and play vital roles in nearly all cellular processes. The term “proteome” refers to all the proteins expressed by a cell or organism under a particular set of conditions. Proteomic analyses can provide insights into the structure and function of proteins, as well as their interactions with other biomolecules.
A variety of proteomic approaches exist, including traditional methods such as two-dimensional gel electrophoresis (2D-GE)